In the last decade, CRISPR/Cas9 gene editing has rapidly evolved from a lab curiosity into a revolutionary medical tool. This technology allows scientists to edit human DNA with unprecedented precision, offering the possibility to cure genetic diseases once deemed incurable medlineplus.gov, news.stanford.edu. In 2023, the first CRISPR-based therapy earned regulatory approval, signaling that the era of gene editing medicine has truly arrived innovativegenomics.org, fda.gov. From sickle cell anemia and cancer to rare metabolic disorders, CRISPR-driven treatments are already transforming lives. At the same time, these breakthroughs have sparked intense ethical debates – about safety, equitable access, and even the prospect of “designer babies.” This report provides an in-depth, up-to-date overview of CRISPR/Cas9 in human medicine: how it works, its applications,