Biotechnologia

Rewinding the Clock: How Yamanaka Factors Are Resetting Aging Cells
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Visszatekerve az órát: Hogyan állítják vissza az öregedő sejteket a Jamanaka-faktorok

Shinya Yamanaka 2006-ban fedezte fel az OSKM faktorokat—Oct4, Sox2, Klf4 és c-Myc—, amelyekkel érett sejteket pluripotens őssejtekké lehet visszaprogramozni. 2016-ban Izpisúa Belmonte és munkatársai részleges in vivo reprogramozást mutattak ki progeria egerekben az OSKM 2–4 napos ciklikus alkalmazásával, pihenőidőkkel, ami 33%-os élettartam-növekedést
augusztus 28, 2025

Technology News

  • Dell, HP and Lenovo push repair-friendly laptops to counter Apple's slimming trend
    January 9, 2026, 3:28 AM EST. Dell, HP and Lenovo are signaling a different path from Apple by designing laptops that are easier to repair or upgrade. The trio's models let users swap batteries, keyboards, RAM and storage, extending lifespans and reducing waste. The shift follows Apple's push for thinner MacBooks with soldered RAM and storage and earlier butterfly keyboard problems. CNET reports that serviceability could reshape product cycles, even as Apple pursues thinner form factors and OLED displays. The move echoes MSI's service-friendly gaming laptops. The question remains whether Apple will adjust its design philosophy to balance form and function.