2015년, 메이요 클리닉과 스크립스 리서치 팀은 다사티닙과 퀘르세틴의 조합이 노령 생쥐의 노화 세포를 선택적으로 제거하여 허약함과 심장 기능을 개선한다는 것을 보여주었습니다. 1세대 세놀리틱에는 다사티닙과 퀘르세틴이 포함되며, 특발성 폐섬유증 및 골관절염과 같은 질환에 대한 인간 안전성 시험에 들어갔습니다. 2024년, 메이요 클리닉 주도의 다사티닙+퀘르세틴
2019년 산업용 효소의 세계 시장은 약 90억 달러였으며, 2027년까지 138억 달러에 이를 것으로 예상됩니다. 1970년대 마이클 스미스가 발명한 부위특이적 돌연변이 유도 기술은 효소의 단일 아미노산을 정밀하게 변경할 수 있게 해주었으며, 그는 이 공로로 1993년 노벨 화학상을 수상했습니다. 1993년 프랜시스 아놀드는 무작위 돌연변이와
신야 야마나카는 2006년에 성숙한 세포를 만능 줄기세포로 재프로그래밍하기 위해 OSKM 인자—Oct4, Sox2, Klf4, c-Myc—를 발견했다. 2016년, 이즈피수아 벨몬테와 동료들은 프로제리아 생쥐에서 OSKM을 2~4일 주기로 투여하고 휴식기를 두는 부분적 생체 내 재프로그래밍을 통해 수명이 33%(18~24주) 연장됨을 보였다. 2020년, 건강한 중년 생쥐에 2일 투여/5일
October 19, 2025, 1:18 PM EDT. As studios chase shorter development cycles, AI is reshaping the game pipeline from concept art to QA. By automating repetitive tasks, accelerating asset creation, and enabling procedural generation, developers can push features to market faster without sacrificing polish. Tools that streamline builds, detect bugs, optimize performance, and simulate player behavior shorten the cycle for blockbuster titles like GTA 6. Yet the shift raises concerns about job displacement and overreliance on automation. The piece surveys practical applications-AI-assisted design, quality assurance, and production scheduling-while underscoring the need for human oversight, ethical safeguards, and robust QA to balance speed with depth of experience.
October 19, 2025, 1:04 PM EDT. Zepp Health (formerly Huami) has pivoted from Xiaomi licensing to focus on its Amazfit wearables. In 2025, the stock has jumped over 1,900%, with most gains in the last quarter, outpacing Apple year to date. The turnaround centers on building the Amazfit brand rather than relying on licensing. Q2 2025 revenue rose 46% year over year to $59 million, driven entirely by Amazfit products. The company has also recruited high-profile ambassadors, like Derrick Henry, to lift brand appeal. While Zepp Health remains unprofitable and riskier than Apple, it could offer upside for investors seeking exposure to smaller wearables makers.
October 19, 2025, 1:02 PM EDT. SpaceX is set to launch a Falcon 9 rocket carrying 28 Starlink satellites from Cape Canaveral Space Force Station at 1:39 p.m. local time, from Space Launch Complex 40. The payload will join dozens of low-Earth orbit satellites, expanding the internet-beaming constellation. This mission marks the 31st flight of the Falcon 9 first-stage booster, continuing SpaceX's record for the most reused rocket in its fleet. After stage separation, SpaceX aims to land the booster on a drone ship in the Atlantic Ocean. The launch underscores SpaceX's ongoing push to grow its satellite internet network and improve coverage globally.
October 19, 2025, 12:20 PM EDT. AI has long been a pain point for Apple, lagging behind rivals in Apple Intelligence features. The revamped Siri did not meet expectations and rollout was delayed. Apple SVP Craig Federighi said the planned Siri revamp failed internal quality checks and aimed for a 2026 rollout. The new Siri is expected with iOS 26.4, about six months away, but Gurman notes engineers remain concerned about performance. Departures hit Apple's foundation models team, with several moving to Meta. Apple is weighing in-house models versus rivals like Anthropic and Google. Two approaches exist: on-device models versus Google Gemini in Private Cloud Compute. WWDC 2024 showed on-screen awareness and cross-app actions, but Siri now leans on ChatGPT for tougher queries amid growing AI startup competition.
October 19, 2025, 12:18 PM EDT. NASA's imaging spectrometer aboard the International Space Station, EMIT, spots a wastewater plume pouring from the Tijuana River into the Pacific. The 620-nanometer spectral feature provides a single, distinctive marker that lets scientists track the plume from orbit along the South Bay shoreline, where millions of gallons flow yearly. In a peer-reviewed study led by Eva Scrivner (University of Connecticut), EMIT signals were matched with lab and estuary spectra, showing very tight correlations (R2 ≥ 0.97) between wastewater concentration and the 620 nm dip. The sensor captures scenes at about 60 meters, offering wide coverage with fine detail. Possible sources behind the dip include phycocyanin in cyanobacteria or chromophoric dissolved organic matter, with researchers still pinning down the exact source.