2015년, 메이요 클리닉과 스크립스 리서치 팀은 다사티닙과 퀘르세틴의 조합이 노령 생쥐의 노화 세포를 선택적으로 제거하여 허약함과 심장 기능을 개선한다는 것을 보여주었습니다. 1세대 세놀리틱에는 다사티닙과 퀘르세틴이 포함되며, 특발성 폐섬유증 및 골관절염과 같은 질환에 대한 인간 안전성 시험에 들어갔습니다. 2024년, 메이요 클리닉 주도의 다사티닙+퀘르세틴
2019년 산업용 효소의 세계 시장은 약 90억 달러였으며, 2027년까지 138억 달러에 이를 것으로 예상됩니다. 1970년대 마이클 스미스가 발명한 부위특이적 돌연변이 유도 기술은 효소의 단일 아미노산을 정밀하게 변경할 수 있게 해주었으며, 그는 이 공로로 1993년 노벨 화학상을 수상했습니다. 1993년 프랜시스 아놀드는 무작위 돌연변이와
신야 야마나카는 2006년에 성숙한 세포를 만능 줄기세포로 재프로그래밍하기 위해 OSKM 인자—Oct4, Sox2, Klf4, c-Myc—를 발견했다. 2016년, 이즈피수아 벨몬테와 동료들은 프로제리아 생쥐에서 OSKM을 2~4일 주기로 투여하고 휴식기를 두는 부분적 생체 내 재프로그래밍을 통해 수명이 33%(18~24주) 연장됨을 보였다. 2020년, 건강한 중년 생쥐에 2일 투여/5일
October 19, 2025, 4:48 PM EDT. Pokémon Legends: Z-A keeps up the franchise's globe-trotting lore by returning to the Hisui-era past first imagined in Pokémon Legends: Arceus. The piece celebrates how that game fused Japanese history aesthetics with Pokémon design-hand-carved pokéballs, brush-stroke battle menus, and woodblock-inspired skies-while giving region-specific looks like the ronin-esque Decidueye and samurai-style Samurott a vivid edge. It also notes the playful link between real places and their poké-versions, from poké-Paris to poké-NYC. But the core angle is the power-and the risk-of time travel in storytelling: Legends: Arceus lets us probe history, prompting questions about representation and how the past is imagined. With Z-A on the horizon, those debates feel newly relevant.
October 19, 2025, 4:46 PM EDT. Apple's new iPad Pro pairs the M5 with on-device AI and a leap in wireless tech. The M5 delivers up to 3.5× faster AI performance and a more energy-efficient chip, aided by a Neural Accelerator in every GPU core. But the standout upgrade is smarter internet and device connectivity thanks to the new C1X modem and N1 wireless controller. Expect faster Wi-Fi 7, Bluetooth 5.2, and Thread, plus up-to 50% faster cellular speeds, GPS, and eSIM. The result: smoother video calls, better multi-device performance, and lower data power use. Preorders start now; official release on October 22, with the M5 powering new iPad Pro, MacBook Pro, and Vision Pro.
October 19, 2025, 4:44 PM EDT. Matic, founded by former Nest engineers, aims to reinvent robot vacuums by mimicking human perception with cameras and neural networks. Crucially, it cleans locally-no cloud connection required-delivering a quieter, more intuitive experience. The result is a robot that looks and works better than many rivals, balancing stellar vacuum performance with a solid mopping capability and a detailed map of your home. It's undeniably charming in a way most gadgets aren't, standing out from the era of clunky Roombas. Yet this premium price is a consideration. If you value cloud-free operation, precise navigation, and a dash of personality, Matic makes a compelling case for the next generation of robotic cleaners.
October 19, 2025, 4:40 PM EDT. Apple is quietly discounting the latest Mac Mini M4 with the M4 chip, now listed at $499 on Amazon, down from $599. This Prime Day-like pricing makes the Mac Mini M4 a compelling choice for budget-conscious buyers who want Apple's performance in a tiny 5 inches by 2 inches chassis. The 16GB of unified memory and a 256GB SSD deliver strong on-device performance, while three Thunderbolt 4 ports, USB-A, HDMI, and Ethernet keep you connected. The fanless design stays quiet on light workloads, with the option to expand storage via Thunderbolt 4. In the Apple ecosystem, features like Continuity, AirDrop, and Sidecar enhance productivity across iPhone and iPad devices, making this compact desktop ideal for home offices and living rooms.
October 19, 2025, 4:38 PM EDT. Apple's iPhone 17 Pro sticks to a polished evolutionary path, bringing a brighter, more color-accurate OLED display, a larger and longer-lasting battery, and the A19 Pro chip paired with 12 GB RAM for standout performance. The camera gains versatility in the telephoto and front modules, though the ultra-wide remains a weak point and the zoom sensor struggles in low light. A shift from titanium to aluminum draws some criticism, with reports of surface scratching and a prominent camera bump. Other caveats include PWM in the display, no high-res audio via Bluetooth, no Auracast, and several iOS 26 features blocked in the EU. Prices start at $1,099 for 256 GB, up to 1 TB. Overall, powerful and long-lasting, but not a dramatic leap.